Causes:
People with cystic fibrosis inherit a defective gene on chromosome 7 called CFTR (cystic fibrosis transmembrane conductance regulator). The protein produced by the gene helps salt movement in and out of cells. Then the protein doesn't work correctly,a thick sticky mucus forms where the salt was incorrectly transferred. . The cells most seriously affected by CF are the lung cells. This mucus clogs the airways in the lungs, and increases the risk of bacterial infection.
People with cystic fibrosis inherit a defective gene on chromosome 7 called CFTR (cystic fibrosis transmembrane conductance regulator). The protein produced by the gene helps salt movement in and out of cells. Then the protein doesn't work correctly,a thick sticky mucus forms where the salt was incorrectly transferred. . The cells most seriously affected by CF are the lung cells. This mucus clogs the airways in the lungs, and increases the risk of bacterial infection.
Cystic fibrosis is a recessive disorder, which means that both parents must pass on the gene for any of their children to get the disease. If a child receives one copy of the gene, he or she will still contract cystic fibrosis. Carriers don't actually have the disease, but they can pass it on to their children.